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Acetazolamida (Diamox) Indications

Acetazolamida is used to treat glaucoma and to treat and to prevent acute mountain sickness (altitude sickness). It is also used as a part of some treatment plans for congestive heart failure and seizure disorders. Acetazolamida is a carbonic anhydrase inhibitor. Carbonic anhydrase is a protein in your body. Acetazolamida reduces the activity of this protein.

How to Use Acetazolamida (Diamox)

Use Acetazolamida as directed by your doctor.

  • Take Acetazolamida by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Drinking extra fluids while you are taking Acetazolamida is recommended.
  • Swallow Acetazolamida whole. Do not break, crush, or chew before swallowing.
  • Acetazolamida may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
  • If you miss a dose of Acetazolamida, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetazolamida.

Storage of Acetazolamida (Diamox)

Store Acetazolamida at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetazolamida out of the reach of children and away from pets.
Acetazolamida (Diamox) Additional Info:

Active Ingredient:Acetazolamide.

Do NOT use Acetazolamida if:

  • you are allergic to any ingredient in Acetazolamida
  • you have adrenal gland problems, low blood levels of potassium or sodium, kidney problems, liver problems (eg, cirrhosis), high blood levels of chloride, or other electrolyte problems.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Acetazolamida. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney stones, a lung disease, glaucoma (eg, chronic non-congestive angle-closure glaucoma), diabetes, or difficulty breathing
  • if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, or dizziness) to any other sulfonamide medicine such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide.

Some medicines may interact with Acetazolamida. Tell your health care provider if you are taking any of the following medicines:

  • Salicylates (eg, aspirin) because they may increase the risk of Acetazolamida's side effects
  • Other carbonic anhydrase inhibitors (eg, methazolamide), cyclosporine, quinidine, phenytoin, amphetamine, or sodium bicarbonate because the risk of their side effects may be increased by Acetazolamida
  • Primidone, salicylates (eg, aspirin), lithium, or methenamine because their effectiveness may be decreased by Acetazolamida.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetazolamida may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Acetazolamida (Diamox) Safety Information

  • Acetazolamida may cause drowsiness or temporary vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use Acetazolamida with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Acetazolamida may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Acetazolamida. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Tell your doctor or dentist that you take Acetazolamida before you receive any medical or dental care, emergency care, or surgery.
  • Diabetes patients - Acetazolamida may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Acetazolamida may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Acetazolamida.
  • Lab tests, including blood electrolyte levels, complete blood cell count, or platelet levels, may be performed while you use Acetazolamida. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Acetazolamida with caution in the elderly; they may be more sensitive to its effects.
  • Acetazolamida should be used with extreme caution in children younger 12 years; safety and effectiveness in these children have not been confirmed.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acetazolamida while you are pregnant. Acetazolamida is found in breast milk. Do not breastfeed while taking Acetazolamida.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Blurred vision; changes in taste; constipation; diarrhea; drowsiness; frequent urination; loss of appetite; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; changes in hearing; convulsions; dark, bloody stools; dark urine; fast breathing; fever; lack of energy; lower back pain; red, swollen, or blistered skin; ringing in the ears; sore throat; tingling of the arms or legs; unusual bleeding or bruising; vision changes; yellowing of the skin or eyes.
 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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This article is written by
Lawanda Durkin, MD.
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