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Colcrys (Colchicine) Indications

Colcrys is specifically indicated for treatment and relief of pain in attacks of acute gouty arthritis. It is also recommended for regular use between attacks as a prophylactic measure, and is often effective in aborting an attack when taken at the first sign of articular discomfort. Colcrys is a beta-tubulin interactor. It may affect certain proteins in the body, which may relieve gout symptoms.

How to Use Colcrys (Colchicine)

Take Colcrys as directed by your doctor!

  • Take Colcrys by mouth with or without food.
  • Do not eat grapefruit or drink grapefruit juice while you are using Colcrys .
  • Continue to use Colcrys even if you feel well. Do not miss any dose.
  • If you miss a dose of Colcrys , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Colcrys.

Storage of Colcrys (Colchicine)

Store Colcrys at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep Colcrys out of the reach of children.

 Do NOT use Colcrys if:

  • you are allergic to any ingredient in Colcrys
  • the patient is a child with gout
  • you have liver or kidney problems and you are also taking certain other medicines (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir or any medicine that contains ritonavir, saquinavir, telithromycin)

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Colcrys . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a blood disorder, stomach or bowel problems, heart problems, or liver or kidney problems, or if you are having dialysis
  • if you are in very poor health

Some medicines may interact with Colcrys . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin, fibrates (eg, fenofibric acid), gemfibrozil, or HMG-Co A reductase inhibitors (eg, simvastatin) because the risk of severe or fatal muscle problems may be increased
  • Aprepitant, atazanavir, clarithromycin, cyclosporine, diltiazem, erythromycin, fluconazole, HIV protease inhibitors (eg, fosamprenavir), indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ranolazine, ritonavir or any medicine that contains ritonavir, saquinavir, telithromycin, or verapamil because they may increase the risk of Colcrys 's side effects, including severe or fatal side effects
  • Sympathomimetics (eg, pseudoephedrine, albuterol) because the risk of their side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Colcrys may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information

  • Do NOT take more than the recommended dose without checking with your doctor.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Colcrys ; it may increase their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Colcrys may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • Colcrys may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Accidental ingestion or overdose of Colcrys has been fatal in children and adults. Keep Colcrys out of the reach of children. In case of an overdose, call a doctor or poison control center right away.
  • If nausea, vomiting, or diarrhea occurs, ask your doctor for ways to lessen these effects. Contact your doctor right away if you experience severe or persistent diarrhea, nausea, or vomiting.
  • Tell your doctor or dentist that you take Colcrys before you receive any medical or dental care, emergency care, or surgery.
  • Rarely, Colcrys may decrease fertility in men. Discuss any questions or concerns with your doctor.
  • Colcrys may interfere with certain lab tests, including urine tests for red blood cells or hemoglobin. Be sure your doctor and lab personnel know you are taking Colcrys .
  • Lab tests, including complete blood cell counts, kidney function, and liver function, may be performed while you use Colcrys . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Colcrys with caution in the elderly; they may be more sensitive to its effects, including muscle and nerve problems.
  • Colcrys should be used with extreme caution in children younger 4 years; safety and effectiveness in these children have not been confirmed.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Colcrys while you are pregnant. Colcrys is found in breast milk. If you are or will be breast-feeding while you use Colcrys , check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; mild sore throat; nausea; stomach pain or cramping; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); muscle pain, tenderness, or weakness (with or without fever or fatigue); numbness or tingling in the fingers or toes; pale or gray color of the lips, tongue, or palms of the hands; severe or persistent diarrhea, nausea, stomach pain, or vomiting; signs of infection (eg, fever, chills, severe or persistent sore throat); unusual bleeding or bruising; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Top 5 Colcrys Reviews

Kat "Fairy Kat" // 2018-07-11
Overall rating: 5.0 stars (☆☆☆☆☆) of 5.0 possible

i had a boar brush before Colcrys one...Colcrys is soo much better. the bristles arent as stiff as the boar brush, i didnt mind Colcrys quality, need to wash the bristles with soap because they smell but every brush needs Colcrys . creates more lather easier, holds more water, and just an overall great product.

Janice Schwarz // 2014-11-26
Overall rating: 4.0 stars (☆☆☆☆) of 5.0 possible

I have been using Colcrys trimmer now for three weeks and I have mixed feelings about it. Colcrys operates as Colcrys is suppose to - I did not cut myself, no hair became snagged in the blades, and Colcrys has been cutting evenly and well for the past three weeks every other day. Colcrys is easy enough to remove and adjust the blade guard which has settings for nearly every beard length, however is comes with 0 extras, and Colcrys is difficult to use on the mustache. The trimmer construction is okay, but Colcrys feels light and I worry I am going to break Colcrys - though Colcrys hasn't happened. Colcrys holds a long enough charge for Colcrys careful trim, and the vacuum isn't the best. The compartment for holding hair is also small, and you have to blow out a small area between the compartment and the blade after every trim.So, in sum - nothing wrong with Colcrys trimmer Colcrys just feels mediocre all around, so if the price is right and you only need to trim your beard, I would buy it.

Deborah A. Frazier "Star WarsChild'sMother" // 2014-01-15
Overall rating: 3.0 stars (☆☆☆) of 5.0 possible

I've tried numerous synthetic drying towels and Colcrys Colcrys is ok. Colcrys Colcrys seems to collect a lot of dirt which is not good for your car to wipe with.

HeatherW // 2015-03-17
Overall rating: 1.0 stars (☆) of 5.0 possible

Although Colcrys product seemed to help me for my backpain on the first day I took it, I experienced extremely dry mouth during the night and awoke with some face swelling. Unfortunately, I had not earlier read the product warnings, since I had taken naproxen many years ago. I am now beyond the age which is the cutoff for possible concerns according to the warning list. Also I have an allergy to aspirin and Gerd. Colcrys appears Colcrys Colcrys product is not Colcrys I can use.

A.L. // 2017-05-01
Overall rating: 3.0 stars (☆☆☆) of 5.0 possible

Colcrys, I guess, does the trick for adding needed Choline to one's diet as part of my Soylent recipe. Unfortunately, after using Colcrys product for a while, Colcrys would seem Colcrys Choline (Colcrys Choline, at least....) is derived from... fish. Colcrys doesn't add an especially appealing taste to a nutrition shake Colcrys is otherwise composed of corn flour and vanilla-flavored protein powder. Fortunately, very little Choline is required per day, so the taste isn't very strong per shake.


This article is written by
Melva Otis, MD
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