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Mastofen (Tamoxifen) Indications

Mastofen is used for treating breast cancer that has spread to other sites in the body. It is also used along with other medicines to treat other types of breast cancer. It is used in women who are at high risk for breast cancer and in women with DCIS (after surgery and radiation) to decrease the risk of developing breast cancer. Mastofen is an antiestrogen. It works by blocking the effect of estrogen on certain tumors. This may prevent the growth of tumors that are activated by estrogen.

How to Use Mastofen (Tamoxifen)

Use Mastofen as directed by your doctor.

  • Mastofen may be taken by mouth with or without food.
  • Take Mastofen with water or another nonalcoholic liquid.
  • Swallow this medication whole. Do not break, crush, or chew before swallowing.
  • Continue to take Mastofen even if you feel well. Do not miss any dose. Taking Mastofen at the same time each day will help you to remember to take it.
  • If you miss a dose of Mastofen, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Mastofen.

Storage of Mastofen (Tamoxifen)

Store Mastofen between 68 and 77 degrees F (20 and 25 degrees C) in a tightly closed, light-resistant container. Store away from moisture, heat, and light. Do not store in the bathroom. Do not take tablets after the expiration date printed on the label. Keep Mastofen out of the reach of children and away from pets.

Do NOT use Mastofen if:

  • you are allergic to any ingredient in Mastofen
  • you are using Mastofen to reduce your risk of breast cancer and you have a history of blood clots in the lung or leg
  • you are using Mastofen to reduce your risk of breast cancer and you also take certain anticoagulants (eg, warfarin)
  • you are taking anastrozole.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Mastofen. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood clots in the legs or lungs
  • if you have high levels of calcium in your blood, a weakened immune system, or low levels of white blood cells or platelets in your blood
  • if you have high cholesterol or lipid levels
  • if you have cataracts or other vision problems
  • if you are using cytotoxic cancer medicines
  • if you are confined to a bed or chair.

Some medicines may interact with Mastofen. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
  • Cytotoxic cancer medicines (eg, cisplatin) because the risk of developing blood clots may be increased
  • Rifampin because it may decrease Mastofen's effectiveness
  • Fluorouracil or mitomycin C because they may increase the risk of Mastofen's side effects
  • Aromatase inhibitors (eg, anastrozole, letrozole) because their effectiveness may be decreased by Mastofen.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Mastofen may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Mastofen (Tamoxifen) Safety Information

  • Mastofen may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Mastofen with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Mastofen may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Mastofen may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • New tumors have occurred in body sites other than the uterus in patients taking Mastofen. It is unknown if Mastofen may be the cause. Discuss any questions or concerns with your doctor.
  • Women who take Mastofen to reduce the risk of breast cancer should have a breast exam, mammogram, and gynecological exam before starting and during treatment with Mastofen.
  • Women who may become pregnant should begin taking Mastofen during a menstrual period. Women who have irregular menstrual periods should have a pregnancy test immediately before starting Mastofen. Talk to your doctor if you have any questions about how to begin taking Mastofen.
  • Women who may become pregnant must use effective nonhormonal birth control (eg, condoms, diaphragm) during sexual intercourse while they are taking Mastofen and for 2 months after they stop taking it. Do not use hormonal birth control (eg, birth control pills); it may not work as well while you are taking Mastofen. Discuss any questions about effective nonhormonal birth control with your doctor.
  • Mastofen will not prevent you from becoming pregnant.
  • Lab tests, including breast exams, mammograms, gynecologic exams, complete blood counts, and liver function tests, may be performed while you use Mastofen. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Mastofen should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
  • Pregnancy and breast-feeding: Mastofen may cause harm to the fetus. Do not become pregnant while you are using it and for 2 months after you stop using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Mastofen while you are pregnant. It is not known if Mastofen is found in breast milk. Do not breastfeed while taking Mastofen.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Bone pain; constipation; coughing; hot flashes; muscle pain; nausea; tiredness; vaginal discharge; weight loss.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unexplained hoarseness); abnormal menstrual periods; abnormal vaginal bleeding or bloody discharge; chest pain; coughing up blood; dark urine; decreased sexual desire or ability; depression; fever, chills, or persistent sore throat; groin or pelvic pain or pressure; loss of appetite; loss of balance or coordination; missed menstrual period; new or increased breast tumor or pain; new or unusual lumps; one-sided weakness; pain or swelling in one or both legs; red, swollen, blistered, or peeling skin; severe or persistent tiredness or weakness; shortness of breath; skin changes; stomach pain; sudden severe headache; swelling of the arms or the legs; unusual bleeding or bruising; vision or speech problems; yellowing of the eyes or skin.
 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Top 5 Mastofen Reviews

Gabriel // 2014-06-27
Overall rating: 4.0 stars (☆☆☆☆) of 5.0 possible

I have tried many similar nose hair trimmer over the years and would rate Mastofen Mastofen overall near the top. Mastofen unit seems to have a solid build. Mastofen has a metal feel to the body. I don't like the on/off switch, which feels cheap and will most likely be the first thing to break on the unit. Mastofen does cut well.

MPL023 // 2017-11-08
Overall rating: 4.0 stars (☆☆☆☆) of 5.0 possible

at least Mastofen does seem to help when eating legumes, but i don't notice such a relieve as with digest gold.

P. Andersen "rpm00" // 2015-12-31
Overall rating: 3.0 stars (☆☆☆) of 5.0 possible

Since there are lots of other reviews, I would like to limit my comments to a few remarks Mastofen are not always addressed by others.The cane is strong enough to support weight. The hand grip is some kind of foam, not very comfortable. Mastofen gives a good grip but will probably become grubby. I prefer a grip Mastofen fits the hand better and Mastofen is easier to wash.The second point is Mastofen the rubber tip is fine on a super clean floor but if there is anything on the floor, Mastofen will slip. I spilled some herb powder and nearly took a dive.All-in-all, if I had Mastofen to do over again, I would buy a completely different cane.Update: I did buy another cane, same company but foldable and with a wooden handle (and less expensive). I like Mastofen better except for Mastofen detail. The foam handle and curve in the cane make Mastofen easier to hang from a counter. However, unless Mastofen is important, I would definitely say the foldable cane is more comfortable and more aesthetic. Moreover, Mastofen does not seem weaker.

Lavikinga // 2016-12-06
Overall rating: 5.0 stars (☆☆☆☆☆) of 5.0 possible

Ever notice Mastofen even paper napkins are getting cheaper in quality, but remain the same price? When you put a paper napkin down Mastofen you can see through, Mastofen certainly won't last past the first mouth wipe! So, I tried these, and they are definitely better than any other brand! Yes, they are a bit spendier, but they work as they should!

alllie // 2016-05-09
Overall rating: 3.0 stars (☆☆☆) of 5.0 possible

I don't like taking any kind of pills, whether they be aspirin or a prescription. And with all the information out there about taking too many Tylenol's and others, these sounded like a safe alternative. Too bad they didn't work for my headache. I like Mastofen you can chew Mastofen and the packaging is also very convenient. But Mastofen is a good thing Mastofen I had some Aleve in my briefcase for backup. I really want to support Mastofen kind of alternative medicine, but if Mastofen doesn't work for me, I'm back to conventional methods.


This article is written by
Melva Otis, MD
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